The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphoenolpyruvate-binding domains
".
FunFam 9: 2-methylisocitrate lyase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylisocitrate lyase activity GO:0046421
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
|
36 |
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
(26 more) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
34 |
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
(24 more) |
|
Oxaloacetase activity GO:0030603
Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate.
|
12 |
A2QP68 (/IDA)
A2QP68 (/IDA)
A2QP68 (/IDA)
A2QP68 (/IDA)
A2QP68 (/IDA)
Q7Z986 (/IDA)
Q7Z986 (/IDA)
Q7Z986 (/IDA)
Q7Z986 (/IDA)
Q7Z986 (/IDA)
(2 more) |
|
Oxo-acid-lyase activity GO:0016833
Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
|
9 | Q83DG5 (/ISS) Q83DG5 (/ISS) Q8EJW1 (/ISS) Q9KSC2 (/ISS) Q9KSC2 (/ISS) Q9KSC2 (/ISS) Q9KSC2 (/ISS) Q9KSC2 (/ISS) Q9KSC2 (/ISS) |
|
Methylisocitrate lyase activity GO:0046421
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
|
6 | Q883R3 (/ISS) Q883R3 (/ISS) Q883R3 (/ISS) Q883R3 (/ISS) Q883R3 (/ISS) Q883R3 (/ISS) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
2 | Q8EJW1 (/ISS) Q937P0 (/ISS) |
|
Lyase activity GO:0016829
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
|
1 | Q5LTE4 (/ISS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
34 |
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
P77541 (/IDA)
(24 more) |
|
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
|
13 |
Q883R3 (/ISS)
Q883R3 (/ISS)
Q883R3 (/ISS)
Q883R3 (/ISS)
Q883R3 (/ISS)
Q883R3 (/ISS)
Q8EJW1 (/ISS)
Q9KSC2 (/ISS)
Q9KSC2 (/ISS)
Q9KSC2 (/ISS)
(3 more) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
13 |
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
Q56062 (/IMP)
(3 more) |
|
Oxalate metabolic process GO:0033609
The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
|
7 | Q7Z986 (/IDA) Q7Z986 (/IDA) Q7Z986 (/IDA) Q7Z986 (/IDA) Q7Z986 (/IDA) Q7Z986 (/IDA) Q7Z986 (/IDA) |
|
Oxaloacetate metabolic process GO:0006107
The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
|
5 | A2QP68 (/IDA) A2QP68 (/IDA) A2QP68 (/IDA) A2QP68 (/IDA) A2QP68 (/IDA) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
3 | Q83DG5 (/ISS) Q83DG5 (/ISS) Q8EJW1 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
3 | O49290 (/IDA) O49290 (/IDA) Q501F7 (/IDA) |
|
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
3 | O49290 (/IDA) O49290 (/IDA) Q501F7 (/IDA) |