The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphoenolpyruvate-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Pyruvate kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyruvate kinase activity GO:0004743
Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate.
240 C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA) C6KTA4 (/IDA)
(230 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
223 P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI)
(213 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
98 P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI) P21599 (/IPI)
(88 more)
Pyruvate kinase activity GO:0004743
Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate.
55 A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS)
(45 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
5 Q93Z53 (/IDA) Q93Z53 (/IDA) Q9FLW9 (/IDA) Q9FLW9 (/IDA) Q9LIK0 (/IDA)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
5 Q93Z53 (/IDA) Q93Z53 (/IDA) Q9FLW9 (/IDA) Q9FLW9 (/IDA) Q9LIK0 (/IDA)
Host cell surface binding GO:0046812
Interacting selectively and non-covalently with the surface of a host cell.
4 Q74JM7 (/IDA) Q74JM7 (/IDA) Q74JM7 (/IDA) Q74JM7 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
223 P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI) P0AD61 (/IPI)
(213 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
125 P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP) P0AD61 (/IMP)
(115 more)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
54 A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS) A0A0J1KMM9 (/ISS)
(44 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
12 C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP) C6KTA4 (/EXP)
(2 more)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
5 Q9FFP6 (/IEP) Q9FFP6 (/IEP) Q9FLW9 (/IEP) Q9FLW9 (/IEP) Q9LIK0 (/IEP)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
3 Q9FLW9 (/IGI) Q9FLW9 (/IGI) Q9LIK0 (/IGI)
Seed maturation GO:0010431
A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.
3 Q9FLW9 (/IMP) Q9FLW9 (/IMP) Q9LIK0 (/IMP)
Seed maturation GO:0010431
A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.
3 Q93Z53 (/ISS) Q93Z53 (/ISS) Q9LIK0 (/ISS)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
2 Q9FLW9 (/IMP) Q9FLW9 (/IMP)
Seed development GO:0048316
The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
2 Q9FLW9 (/IMP) Q9FLW9 (/IMP)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
1 Q9VD23 (/ISS)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
232 O51323 (/IDA) O51323 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA) P0AD61 (/IDA)
(222 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
230 P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA)
(220 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
125 P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA) P0AD61 (/HDA)
(115 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P9WKE5 (/HDA) P9WKE5 (/HDA) P9WKE5 (/HDA) P9WKE5 (/HDA) P9WKE5 (/HDA) P9WKE5 (/HDA) P9WKE5 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
5 Q93Z53 (/IDA) Q93Z53 (/IDA) Q9FLW9 (/IDA) Q9FLW9 (/IDA) Q9LIK0 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
5 Q93Z53 (/IDA) Q93Z53 (/IDA) Q9FLW9 (/IDA) Q9FLW9 (/IDA) Q9LIK0 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 B1B1P9 (/IDA) Q9FLW9 (/IDA) Q9FLW9 (/IDA) Q9M057 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9FFP6 (/IDA) Q9FFP6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9VD23 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9VD23 (/ISS)
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
1 B1B1P9 (/IDA)
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