The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Radical SAM ThiC family, central domain
".
FunFam 1: Phosphomethylpyrimidine synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
11 |
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
(1 more) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | O82392 (/IPI) |
|
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
|
1 | O82392 (/IDA) |
|
ADP-ribose pyrophosphohydrolase activity GO:0080041
Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.
|
1 | O82392 (/IGI) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
32 |
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
(22 more) |
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
11 |
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q81WY7 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
Q9KVS8 (/ISS)
(1 more) |
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
1 | O82392 (/IMP) |
|
Response to vitamin B1 GO:0010266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.
|
1 | O82392 (/IEP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
32 |
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
P30136 (/IDA)
(22 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
11 |
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
(1 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
11 |
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
P9WG79 (/HDA)
(1 more) |
|
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
1 | O82392 (/IDA) |
|
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
|
1 | O82392 (/IDA) |
|
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
1 | O82392 (/IDA) |
