The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EAL domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Bifunctional diguanylate cyclase/phosphodiesterase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Diguanylate cyclase activity GO:0052621
Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).
11 P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA)
(1 more)
Cyclic-guanylate-specific phosphodiesterase activity GO:0071111
Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).
11 P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA)
(1 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cyclic nucleotide biosynthetic process GO:0009190
The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
11 P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA)
(1 more)
Cyclic nucleotide catabolic process GO:0009214
The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
11 P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA) P9WM13 (/IDA)
(1 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA) P9WM13 (/HDA)
(1 more)
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