The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FMN-linked oxidoreductases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Heptaprenylglyceryl phosphate synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heptaprenylglyceryl phosphate synthase. [EC: 2.5.1.n9]
All-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(all-trans-heptaprenyl)glycerol 1-phosphate.
  • Part of the pathway in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
1297 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6 A0A023P0H6
(1287 more...)
Phosphoglycerol geranylgeranyltransferase. [EC: 2.5.1.41]
Geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate.
  • Catalyzes the first pathway-specific step in the biosynthesis of the core membrane diether lipids in archaebacteria.
  • It catalyzes the alkylation of the primary hydroxy group in sn-glycerol 1-phosphate by geranylgeranyl diphosphate (GGPP) in a prenyltransfer reaction where a hydroxy group is the nucleophile in the acceptor substrate.
  • The other enzymes involved in the biosynthesis of polar lipids in archaea are EC 1.1.1.261, EC 2.5.1.42 and EC 2.7.7.67, which lead to the formation of CDP-unsaturated archaeol.
  • The final step in the pathway involves the addition of L-serine, with concomitant removal of CMP, leading to the production of unsaturated archaetidylserine.
100 A0A0E3LKI5 A0A0E3LKI5 A0A0E3MIW3 A0A0E3MIW3 A0A0E3RGU7 A0A0E3RGU7 A0A0E3RGU7 A0A0F8TMQ2 A0A0F8TMQ2 A0A0F8TMQ2
(90 more...)
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