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CATH Superfamily 3.20.20.330

Homocysteine-binding-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homocysteine-binding-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Bifunctional homocysteine S-methyltransferase/meth...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Homocysteine S-methyltransferase. [EC: 2.1.1.10]
S-methyl-L-methionine + L-homocysteine = 2 L-methionine.
  • The enzyme uses S-adenosyl-L-methionine as methyl donor less actively than S-methyl-L-methionine.
 36 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A165B5L8 A0A165B5L8 A0A165B5L8 A0A165B5L8
(26 more...)
Methylenetetrahydrofolate reductase (NAD(P)H). [EC: 1.5.1.20]
5-methyltetrahydrofolate + NAD(P)(+) = 5,10-methylenetetrahydrofolate + NAD(P)H.
  • Menadione can also serve as an electron acceptor.
  • Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5.
 36 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A0T8PPH4 A0A165B5L8 A0A165B5L8 A0A165B5L8 A0A165B5L8
(26 more...)