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CATH Superfamily 3.20.20.30

Luciferase-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Luciferase-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39: Alkanal monooxygenase beta chain

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Bacterial luciferase. [EC: 1.14.14.3]
A long-chain aldehyde + FMNH(2) + O(2) = a long-chain fatty acid + FMN + H(2)O + light.
  • The reaction sequence starts with the incorporation of a molecule of oxygen into reduced FMN bound to the enzyme, forming luciferase peroxyflavin.
  • The peroxyflavin interacts with an aliphatic long-chain aldehyde, producing a highly fluorescent species believed to be luciferase hydroxyflavin.
  • The enzyme is highly specific for reduced FMN and for long-chain aliphatic aldehydes with eight carbons or more.
  • The highest efficiency is achieved with tetradecanal.
  • Cf. EC 1.13.12.18.
 4 C5I984 C5I984 P19908 P19908
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