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CATH Superfamily 3.20.20.220

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: Proline dehydrogenase 2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Proline dehydrogenase. [EC: 1.5.5.2]
L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol.
  • The electrons from L-proline are transferred to the FAD cofactor, and from there to a quinone acceptor.
  • In many organisms, ranging from bacteria to mammals, proline is oxidized to glutamate in a two-step process involving this enzyme and EC 1.2.1.88.
  • Both activities are carried out by the same enzyme in enterobacteria.
  • Formerly EC 1.5.99.8.
 26 A0A0A1LSZ1 A0A0A1LSZ1 A0A0A1LSZ1 A0A0A1LSZ1 A0A0A1LSZ1 A0A0T8PUI4 A0A0T8PUI4 A0A0T8PUI4 A0A0T8PUI4 A0A0T8PUI4
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