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CATH Superfamily 3.20.20.150

Divalent-metal-dependent TIM barrel enzymes

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Divalent-metal-dependent TIM barrel enzymes
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Mannonate dehydratase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
 14 P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA)
(4 more)
Mannonate dehydratase activity GO:0008927
Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
 14 P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA)
(4 more)
Mannonate dehydratase activity GO:0008927
Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
 14 P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP)
(4 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
 14 P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA) P24215 (/IDA)
(4 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
 14 P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP) P24215 (/IEP)
(4 more)
D-glucuronate catabolic process GO:0042840
The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.
 14 P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP) P24215 (/IMP)
(4 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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