The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39: Adenine deaminase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
22 E9AF40 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA)
(12 more)
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
11 P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI)
(1 more)
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
10 P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI) P53909 (/IPI)
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
1 Q9P6J8 (/ISS)
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
1 Q8X1T6 (/RCA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine catabolic process GO:0006146
The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
12 P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA)
(2 more)
Adenine catabolic process GO:0006146
The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
11 P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI) P53909 (/IGI)
(1 more)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
11 E9AF40 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP)
(1 more)
Hypoxanthine salvage GO:0043103
Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.
11 P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA)
(1 more)
Adenine catabolic process GO:0006146
The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
10 P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
10 P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA) P53909 (/IDA)
Hypoxanthine salvage GO:0043103
Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.
10 P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP) P53909 (/IMP)
Purine nucleobase catabolic process GO:0006145
The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
1 Q8X1T6 (/IEP)
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
1 Q9P6I7 (/IMP)
Cell-abiotic substrate adhesion GO:0036164
The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.
1 Q59ZB1 (/IMP)
Nucleotide salvage GO:0043173
Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
1 Q8X1T6 (/RCA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA) P53909 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9P6I7 (/HDA) Q9P6J8 (/HDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 E9AF40 (/IMP)
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