The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22: Guanine deaminase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanine deaminase activity GO:0008892
Catalysis of the reaction: guanine + H2O = xanthine + NH3.
11 P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) Q07729 (/IDA) Q07729 (/IDA) Q07729 (/IDA) Q07729 (/IDA)
(1 more)
Guanine deaminase activity GO:0008892
Catalysis of the reaction: guanine + H2O = xanthine + NH3.
7 O14057 (/ISS) Q48KR9 (/ISS) Q48KR9 (/ISS) Q48KR9 (/ISS) Q5LP92 (/ISS) Q87YX9 (/ISS) Q87YX9 (/ISS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA) P76641 (/IDA)
Ammeline aminohydrolase activity GO:0018756
Catalysis of the reaction: ammeline + H2O = ammelide + NH3.
6 P76641 (/IMP) P76641 (/IMP) P76641 (/IMP) P76641 (/IMP) P76641 (/IMP) P76641 (/IMP)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
4 Q07729 (/ISS) Q07729 (/ISS) Q07729 (/ISS) Q07729 (/ISS)
Dihydropterin deaminase activity GO:0004153
Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.
1 Q9VMY9 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanine metabolic process GO:0046098
The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
4 Q07729 (/ISS) Q07729 (/ISS) Q07729 (/ISS) Q07729 (/ISS)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 A0A1D8PQQ8 (/IMP) A0A1D8PQQ8 (/IMP)
Purine nucleotide catabolic process GO:0006195
The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 Q5LP92 (/ISS)
Eye pigment biosynthetic process GO:0006726
The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
1 Q9VMY9 (/IMP)
Guanine metabolic process GO:0046098
The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
1 Q9VMY9 (/IMP)
Dihydropteridine metabolic process GO:0051067
The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.
1 Q9VMY9 (/IDA)
Dihydropteridine metabolic process GO:0051067
The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.
1 Q9VMY9 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q07729 (/HDA) Q07729 (/HDA) Q07729 (/HDA) Q07729 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 Q2UHY8 (/IDA) Q2UHY8 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O14057 (/HDA)
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