The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: 3'-5' ssDNA/RNA exonuclease TatD

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Deoxyribonuclease activity GO:0004536
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
12 G5EG18 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(2 more)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Single-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008310
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
11 P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA) P27859 (/RCA)
(1 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA catabolic process, exonucleolytic GO:0000738
The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
11 P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP) P27859 (/IMP)
(1 more)
RNA phosphodiester bond hydrolysis GO:0090501
The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Apoptotic DNA fragmentation GO:0006309
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
1 G5EG18 (/IDA)
Apoptotic DNA fragmentation GO:0006309
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
1 G5EG18 (/IGI)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 G5EG18 (/IMP)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
1 G5EG18 (/HEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA) P27859 (/IDA)
(1 more)
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