The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Adenine deaminase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
16 P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA)
(6 more)
Adenine deaminase activity GO:0000034
Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
16 P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP)
(6 more)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
16 P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA)
(6 more)
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
16 P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA)
(6 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
16 P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA) P31441 (/IDA)
(6 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine catabolic process GO:0006146
The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
16 P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP)
(6 more)
Hypoxanthine biosynthetic process GO:0046101
The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
16 P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP) P31441 (/IMP)
(6 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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