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CATH Superfamily 3.20.20.140

Metal-dependent hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: 5-methylthioadenosine/S-adenosylhomocysteine deami...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
S-methyl-5'-thioadenosine deaminase. [EC: 3.5.4.31]
S-methyl-5'-thioadenosine + H(2)O = S-methyl-5'-thioinosine + NH(3).
  • The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28) and has some activity against adenosine.
  • Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are not substrates.
  • Formerly EC 3.5.4.n1.
 95 A0A0E3QKP3 A0A0E3QKP3 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0
(85 more...)
S-adenosylhomocysteine deaminase. [EC: 3.5.4.28]
S-adenosyl-L-homocysteine + H(2)O = S-inosyl-L-homocysteine + NH(3).
    		 95 A0A0E3QKP3 A0A0E3QKP3 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0
    (85 more...)
    Adenosine deaminase. [EC: 3.5.4.4]
    Adenosine + H(2)O = inosine + NH(3).
      		 22 A0A0E3QKP3 A0A0E3QKP3 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0
      (12 more...)
      5'-deoxyadenosine deaminase. [EC: 3.5.4.41]
      5'-deoxyadenosine + H(2)O = 5'-deoxyinosine + NH(3).
      • The enzyme from the archaeon Methanocaldococcus jannaschii is involved in the recycling of 5'-deoxyadenosine.
      		 22 A0A0E3QKP3 A0A0E3QKP3 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RL84 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0 A0A0E3RTF0
      (12 more...)
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