The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Queuine tRNA-ribosyltransferase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Queuine tRNA-ribosyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Queuine tRNA-ribosyltransferase activity GO:0008479
Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
165 P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA)
(155 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
161 P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA)
(151 more)
Queuine tRNA-ribosyltransferase activity GO:0008479
Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
13 Q28HC6 (/ISS) Q4QQY7 (/ISS) Q4QR99 (/ISS) Q7SYK1 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS)
(3 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 Q28HC6 (/ISS) Q4QQY7 (/ISS) Q4QR99 (/ISS) Q7SYK1 (/ISS) Q9JMA2 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
5 Q28HC6 (/ISS) Q4QQY7 (/ISS) Q4QR99 (/ISS) Q7SYK1 (/ISS) Q9JMA2 (/ISS)
Queuine tRNA-ribosyltransferase activity GO:0008479
Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
4 Q4QR99 (/TAS) Q9BXR0 (/TAS) Q9BXR0 (/TAS) Q9BXR0 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q9BXR0 (/IDA) Q9BXR0 (/IDA) Q9BXR0 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 Q9BXR0 (/IDA) Q9BXR0 (/IDA) Q9BXR0 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9JMA2 (/IPI)
Queuine tRNA-ribosyltransferase activity GO:0008479
Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
1 O94460 (/ISM)
Queuine tRNA-ribosyltransferase activity GO:0008479
Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
1 Q9JMA2 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9JMA2 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q9JMA2 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA wobble guanine modification GO:0002099
The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
161 P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP)
(151 more)
Queuosine biosynthetic process GO:0008616
The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
161 P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP) P0A847 (/IMP)
(151 more)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
9 Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS) Q9KTY9 (/ISS)
TRNA-guanine transglycosylation GO:0101030
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
4 Q9BXR0 (/IDA) Q9BXR0 (/IDA) Q9BXR0 (/IDA) Q9JMA2 (/IDA)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
3 Q9BXR0 (/TAS) Q9BXR0 (/TAS) Q9BXR0 (/TAS)
TRNA-guanine transglycosylation GO:0101030
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
3 Q9BXR0 (/NAS) Q9BXR0 (/NAS) Q9BXR0 (/NAS)
Queuosine biosynthetic process GO:0008616
The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
1 Q4QR99 (/TAS)
TRNA-guanine transglycosylation GO:0101030
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
1 O94460 (/IMP)
TRNA-guanine transglycosylation GO:0101030
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
1 Q9JMA2 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
161 P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA) P0A847 (/IDA)
(151 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
4 Q9BXR0 (/IPI) Q9BXR0 (/IPI) Q9BXR0 (/IPI) Q9JMA2 (/IPI)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
3 Q9BXR0 (/TAS) Q9BXR0 (/TAS) Q9BXR0 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O94460 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JMA2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9JMA2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94460 (/HDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9JMA2 (/ISO)
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