The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADP-dependent oxidoreductase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32: Hyperkinetic, isoform I

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
9 M9NEC7 (/ISS) M9NF11 (/ISS) M9NGY7 (/ISS) M9PE66 (/ISS) M9PGS8 (/ISS) M9PHI0 (/ISS) Q24052 (/ISS) Q9W2W9 (/ISS) Q9W2X0 (/ISS)
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
9 M9NEC7 (/IMP) M9NF11 (/IMP) M9NGY7 (/IMP) M9PE66 (/IMP) M9PGS8 (/IMP) M9PHI0 (/IMP) Q24052 (/IMP) Q9W2W9 (/IMP) Q9W2X0 (/IMP)
Aldo-keto reductase (NADP) activity GO:0004033
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.
1 M9PHI0 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 M9NEC7 (/IDA) M9NF11 (/IDA) M9NGY7 (/IDA) M9PE66 (/IDA) M9PGS8 (/IDA) M9PHI0 (/IDA) Q24052 (/IDA) Q9W2W9 (/IDA) Q9W2X0 (/IDA)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 M9NEC7 (/ISS) M9NF11 (/ISS) M9NGY7 (/ISS) M9PE66 (/ISS) M9PGS8 (/ISS) M9PHI0 (/ISS) Q24052 (/ISS) Q9W2W9 (/ISS) Q9W2X0 (/ISS)
Positive regulation of circadian sleep/wake cycle, sleep GO:0045938
Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
9 M9NEC7 (/IMP) M9NF11 (/IMP) M9NGY7 (/IMP) M9PE66 (/IMP) M9PGS8 (/IMP) M9PHI0 (/IMP) Q24052 (/IMP) Q9W2W9 (/IMP) Q9W2X0 (/IMP)
Circadian sleep/wake cycle, sleep GO:0050802
The part of the circadian sleep/wake cycle where the organism is asleep.
9 M9NEC7 (/IDA) M9NF11 (/IDA) M9NGY7 (/IDA) M9PE66 (/IDA) M9PGS8 (/IDA) M9PHI0 (/IDA) Q24052 (/IDA) Q9W2W9 (/IDA) Q9W2X0 (/IDA)
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
9 M9NEC7 (/IPI) M9NF11 (/IPI) M9NGY7 (/IPI) M9PE66 (/IPI) M9PGS8 (/IPI) M9PHI0 (/IPI) Q24052 (/IPI) Q9W2W9 (/IPI) Q9W2X0 (/IPI)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
9 M9NEC7 (/IPI) M9NF11 (/IPI) M9NGY7 (/IPI) M9PE66 (/IPI) M9PGS8 (/IPI) M9PHI0 (/IPI) Q24052 (/IPI) Q9W2W9 (/IPI) Q9W2X0 (/IPI)
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
9 M9NEC7 (/ISS) M9NF11 (/ISS) M9NGY7 (/ISS) M9PE66 (/ISS) M9PGS8 (/ISS) M9PHI0 (/ISS) Q24052 (/ISS) Q9W2W9 (/ISS) Q9W2X0 (/ISS)
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