The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADP-dependent oxidoreductase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Aldo/keto reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
3 A6KWY2 (/IDA) A6KWY2 (/IDA) A6KWY2 (/IDA)
L-galactose dehydrogenase activity GO:0010349
Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.
2 O81884 (/IDA) O81884 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-ascorbic acid biosynthetic process GO:0019853
The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-
2 O81884 (/IMP) O81884 (/IMP)
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
1 Q20127 (/IGI)
Detection of mechanical stimulus involved in sensory perception of touch GO:0050976
The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
1 Q20127 (/IGI)
Positive regulation of detection of mechanical stimulus involved in sensory perception of touch GO:1905789
Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
1 Q20127 (/IGI)
Positive regulation of mechanosensory behavior GO:1905792
Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.
1 Q20127 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O81884 (/IDA) O81884 (/IDA)
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