The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aconitase, domain 4
".
FunFam 3: 3-isopropylmalate dehydratase small subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
95 |
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
P30126 (/IPI)
(85 more) |
|
Intramolecular transferase activity GO:0016866
Catalysis of the transfer of a functional group from one position to another within a single molecule.
|
93 |
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
(83 more) |
|
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
|
8 | Q8E9N5 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) |
|
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
|
2 | P07264 (/IMP) P07264 (/IMP) |
|
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
|
2 | Q5B0P4 (/RCA) Q5B0P4 (/RCA) |
|
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
|
2 | P49367 (/ISA) P49367 (/ISA) |
|
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
|
1 | O14289 (/ISO) |
|
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
|
1 | Q92412 (/IDA) |
|
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
|
1 | Q92412 (/IMP) |
|
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
|
1 | Q9UT74 (/ISO) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
|
93 |
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
(83 more) |
|
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
|
16 |
P07264 (/IMP)
P07264 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
P9WK95 (/IMP)
(6 more) |
|
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
|
8 | Q8E9N5 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) |
|
Lysine biosynthetic process via aminoadipic acid GO:0019878
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
|
4 | P49367 (/IMP) P49367 (/IMP) Q92412 (/IMP) Q9UT74 (/IMP) |
|
Lysine biosynthetic process GO:0009085
The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
|
3 | Q4WUL6 (/IMP) Q5A644 (/IMP) Q9UT74 (/IMP) |
|
Branched-chain amino acid metabolic process GO:0009081
The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
2 | Q5B0P4 (/RCA) Q5B0P4 (/RCA) |
|
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
|
2 | Q5B0P4 (/IEP) Q5B0P4 (/IEP) |
|
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
1 | Q9UT74 (/NAS) |
|
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
|
1 | O14289 (/EXP) |
|
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
|
1 | Q4WUL6 (/IEP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
95 |
P07264 (/IDA)
P07264 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
P30126 (/IDA)
(85 more) |
|
3-isopropylmalate dehydratase complex GO:0009316
A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
|
93 |
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
P30126 (/IMP)
(83 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
12 |
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
P9WK95 (/HDA)
(2 more) |
|
3-isopropylmalate dehydratase complex GO:0009316
A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
|
7 | Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) Q9KP80 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | P49367 (/HDA) P49367 (/HDA) Q9UT74 (/HDA) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
2 | P07264 (/IDA) P07264 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9UT74 (/IMP) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O14289 (/ISO) |