The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
D-amino Acid Aminotransferase, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Branched-chain-amino-acid aminotransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Branched-chain-amino-acid transaminase activity GO:0004084
Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
10 P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P47176 (/IDA) P47176 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P38891 (/IPI) P47176 (/IPI) P47176 (/IPI)
Branched-chain-amino-acid transaminase activity GO:0004084
Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
2 Q5B0H3 (/ISA) Q5B0H3 (/ISA)
Branched-chain-amino-acid transaminase activity GO:0004084
Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
2 Q5B0H3 (/RCA) Q5B0H3 (/RCA)
Branched-chain-amino-acid transaminase activity GO:0004084
Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
1 Q54N47 (/ISS)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
1 O14370 (/ISS)
L-leucine transaminase activity GO:0052654
Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.
1 O14370 (/IGI)
L-valine transaminase activity GO:0052655
Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.
1 O14370 (/IGI)
L-isoleucine transaminase activity GO:0052656
Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.
1 O14370 (/IGI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
10 P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P47176 (/IDA) P47176 (/IDA)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
10 P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P47176 (/IMP) P47176 (/IMP)
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
10 P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P38891 (/IMP) P47176 (/IMP) P47176 (/IMP)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
3 Q586R0 (/ISA) Q586R0 (/ISA) Q586R1 (/ISA)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
3 Q586R1 (/ISA) Q5B0H3 (/ISA) Q5B0H3 (/ISA)
Branched-chain amino acid metabolic process GO:0009081
The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2 Q5B0H3 (/RCA) Q5B0H3 (/RCA)
Cellular amino acid catabolic process GO:0009063
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
1 Q54N47 (/ISS)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
1 Q54N47 (/ISS)
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
1 O14370 (/IGI)
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
1 O14370 (/IGI)
Valine biosynthetic process GO:0009099
The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
1 O14370 (/IGI)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 P38891 (/HDA) P38891 (/HDA) P38891 (/HDA) P38891 (/HDA) P38891 (/HDA) P38891 (/HDA) P38891 (/HDA) P38891 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
8 P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA) P38891 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P47176 (/IDA) P47176 (/IDA) Q586R0 (/IDA) Q586R0 (/IDA) Q586R1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O14370 (/HDA) P47176 (/HDA) P47176 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q586R0 (/ISA) Q586R0 (/ISA) Q586R1 (/ISA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q586R0 (/RCA) Q586R0 (/RCA) Q586R1 (/RCA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
3 Q586R0 (/IDA) Q586R0 (/IDA) Q586R1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q586R0 (/IDA) Q586R0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P47176 (/HDA) P47176 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 E9ADI3 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 E9ADI3 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 O14370 (/IGI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O14370 (/HDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q586R1 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 E9ADI3 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 E9ADI3 (/ISO)