The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CBS-domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Glycine betaine/L-proline ABC transporter ATP-bind...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Osmosensor activity GO:0005034
Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.
78 P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM)
(68 more)
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
78 P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA)
(68 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
78 P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI) P14175 (/IPI)
(68 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
78 P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM)
(68 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
80 P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA) P17328 (/IDA)
(70 more)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
78 P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA)
(68 more)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
78 P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP) P14175 (/IEP)
(68 more)
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
78 P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA) P14175 (/IDA)
(68 more)
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
78 P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS) P14175 (/TAS)
(68 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
78 P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM) P14175 (/ISM)
(68 more)