The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CBS-domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 34: Glycine betaine/choline ABC transporter ATP-bindin...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
5 Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS)
Carnitine transmembrane transporter activity GO:0015226
Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
5 Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS)
ATPase-coupled quaternary ammonium compound transmembrane transporting activity GO:0015418
Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in).
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)
ATPase-coupled glycine betaine transporter activity GO:0031459
Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)
ATPase-coupled choline transmembrane transporter activity GO:0033266
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
5 Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amine transport GO:0015837
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
Amino-acid betaine transport GO:0015838
The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)
Cellular hyperosmotic salinity response GO:0071475
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
19 Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS) Q87WH5 (/ISS)
(9 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
5 Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA)