The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: NTF2-related export protein 2 isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
20 Q3UNA4 (/IPI) Q9NPJ8 (/IPI) Q9NPJ8 (/IPI) Q9QZV9 (/IPI) Q9U757 (/IPI) Q9UKK6 (/IPI) Q9UKK6 (/IPI) Q9UKK6 (/IPI) Q9UKK6 (/IPI) Q9UKK6 (/IPI)
(10 more)
Ran GTPase binding GO:0008536
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
1 Q9QZV9 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
15 Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS)
(5 more)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
4 A0A140LG28 (/IMP) E9QCN6 (/IMP) F1QNZ5 (/IMP) Q0P4D8 (/IMP)
MRNA transport GO:0051028
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 A0A140LG28 (/IGI) E9QCN6 (/IGI) F1QNZ5 (/IGI) Q0P4D8 (/IGI)
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
2 Q9V3H8 (/IMP) Q9V3H8 (/IMP)
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
2 Q9V3H8 (/HMP) Q9V3H8 (/HMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
2 Q9V3H8 (/HMP) Q9V3H8 (/HMP)
RNA export from nucleus GO:0006405
The directed movement of RNA from the nucleus to the cytoplasm.
1 Q9QZV9 (/IDA)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
1 Q9QZV9 (/IDA)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
19 Q9NPJ8 (/IDA) Q9NPJ8 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 Q9NPJ8 (/IDA) Q9NPJ8 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA) Q9UKK6 (/IDA)
(7 more)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
15 Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS)
(5 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
15 Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS)
(5 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
15 Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS) Q9UKK6 (/TAS)
(5 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
6 A6QNX3 (/ISS) B2GV77 (/ISS) Q5ZLH0 (/ISS) Q5ZLH0 (/ISS) Q9NPJ8 (/ISS) Q9NPJ8 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 A6QNX3 (/ISS) B2GV77 (/ISS) Q5ZLH0 (/ISS) Q5ZLH0 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A6QNX3 (/ISS) B2GV77 (/ISS) Q5ZLH0 (/ISS) Q5ZLH0 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q3UNA4 (/IDA) Q9V3H8 (/IDA) Q9V3H8 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 Q9V3H8 (/IDA) Q9V3H8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q3UNA4 (/ISO) Q9QZV9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q3UNA4 (/ISO) Q9QZV9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q3UNA4 (/IDA)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
1 Q9QZV9 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q3UNA4 (/IDA)
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