The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 44: Ubiquitin-fold modifier 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
76 P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI) P61960 (/IPI)
(66 more)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
132 B0G186 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B5LVL2 (/ISS) B5LVL2 (/ISS) B9ENM6 (/ISS) B9ENM6 (/ISS) C1BJ98 (/ISS) P61961 (/ISS)
(122 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
117 P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS)
(107 more)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
117 P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS) P61961 (/ISS)
(107 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
93 B3DL37 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B5LVL2 (/ISS) B5LVL2 (/ISS) B9ENM6 (/ISS) B9ENM6 (/ISS) C1BJ98 (/ISS) Q2KJG2 (/ISS) Q2KJG2 (/ISS)
(83 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
83 A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) Q2KJG2 (/ISS) Q2KJG2 (/ISS) Q4R4I2 (/ISS) Q4R4I2 (/ISS) Q4R4I2 (/ISS) Q4R4I2 (/ISS)
(73 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
76 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(66 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
38 P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP)
(28 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
38 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(28 more)
Regulation of intracellular estrogen receptor signaling pathway GO:0033146
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
38 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(28 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
38 P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP) P61961 (/IMP)
(28 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
38 P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS)
(28 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
38 P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP) P61960 (/IMP)
(28 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
38 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(28 more)
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Protein modification by small protein conjugation GO:0032446
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
5 Q4QER1 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO)
Neuromuscular process GO:0050905
Any process pertaining to the functions of the nervous and muscular systems of an organism.
4 A8DYH2 (/IMP) A8DYH2 (/IMP) A8DYH2 (/IMP) A8DYH2 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q5BJP3 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
136 A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) B0G186 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B5LVL2 (/ISS) B5LVL2 (/ISS)
(126 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
136 A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) A8DYH2 (/ISS) B0G186 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B3DL37 (/ISS) B5LVL2 (/ISS) B5LVL2 (/ISS)
(126 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
76 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(66 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
76 P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA) P61960 (/IDA)
(66 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
38 P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO) P61961 (/ISO)
(28 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
38 P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA) P61961 (/IDA)
(28 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
38 P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS) P61960 (/ISS)
(28 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 Q4QER1 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO) Q57UL0 (/ISO)
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