The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 348: DNA damage-inducible protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
7 P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P40087 (/IPI) P40087 (/IPI) P40087 (/IPI) P40087 (/IPI) P40087 (/IPI) P40087 (/IPI) P40087 (/IPI)
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
7 P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
7 P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
7 P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
7 P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043328
The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.
7 P40087 (/IGI) P40087 (/IGI) P40087 (/IGI) P40087 (/IGI) P40087 (/IGI) P40087 (/IGI) P40087 (/IGI)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043328
The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.
7 P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP) P40087 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA) P40087 (/IDA)
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