CATH Superfamily 3.10.20.90
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".
FunFam 322: Uncharacterized protein, isoform D
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q0KHR3 (/IPI) X2JCB3 (/IPI) |
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Phosphatidic acid binding GO:0070300
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Morphogenesis of a polarized epithelium GO:0001738
The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Cell-cell junction assembly GO:0007043
The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Germarium-derived oocyte fate determination GO:0007294
The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Ovarian follicle cell-cell adhesion GO:0007299
The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Oocyte anterior/posterior axis specification GO:0007314
Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Germ-band extension GO:0007377
Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Germ-band extension GO:0007377
Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Asymmetric cell division GO:0008356
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Photoreceptor cell morphogenesis GO:0008594
The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Oocyte microtubule cytoskeleton organization GO:0016325
Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Establishment or maintenance of polarity of embryonic epithelium GO:0016332
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Border follicle cell delamination GO:0030709
The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Establishment of apical/basal cell polarity GO:0035089
The specification and formation of the polarity of a cell along its apical/basal axis.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Establishment or maintenance of neuroblast polarity GO:0045196
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Negative regulation of filopodium assembly GO:0051490
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
|
2 | Q0KHR3 (/IGI) X2JCB3 (/IGI) |
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Branching involved in open tracheal system development GO:0060446
The process in which the anatomical structures of branches in the open tracheal system are generated and organized.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Malpighian tubule development GO:0072002
The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
|
2 | Q0KHR3 (/IMP) X2JCB3 (/IMP) |
Regulation of establishment of planar polarity GO:0090175
Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
|
2 | Q0KHR3 (/IGI) X2JCB3 (/IGI) |
Axis elongation GO:0003401
The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.
|
1 | Q0KHR3 (/IDA) |
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
1 | Q0KHR3 (/IMP) |
Cell-cell adhesion involved in establishment of planar polarity GO:0090250
The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity.
|
1 | Q0KHR3 (/IDA) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Spot adherens junction GO:0005914
A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Zonula adherens GO:0005915
A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Apical junction complex GO:0043296
A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
|
2 | Q0KHR3 (/IDA) X2JCB3 (/IDA) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
2 | Q0KHR3 (/NAS) X2JCB3 (/NAS) |
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
2 | Q0KHR3 (/TAS) X2JCB3 (/TAS) |
Cytoplasmic side of apical plasma membrane GO:0098592
The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
|
1 | Q0KHR3 (/IDA) |