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CATH Superfamily 3.10.20.90

Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Polyubiquitin 10

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 45 P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI) P0CG63 (/IPI)
(35 more)
Protein tag GO:0031386
A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.
 40 P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA)
(30 more)
ATP-dependent protein binding GO:0043008
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP.
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
Protein tag GO:0031386
A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.
 5 P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
 45 Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS)
(35 more)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
Protein monoubiquitination GO:0006513
Addition of a single ubiquitin group to a protein.
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
 40 P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA) P0CG63 (/IDA)
(30 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
 40 P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP) P0CG63 (/IMP)
(30 more)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
 15 P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS) P0CH32 (/TAS)
(5 more)
Proteasomal ubiquitin-independent protein catabolic process GO:0010499
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.
 5 P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS) P0CG72 (/NAS)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
 5 P0CG72 (/IMP) P0CG72 (/IMP) P0CG72 (/IMP) P0CG72 (/IMP) P0CG72 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
 45 Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS) Q7KQK2 (/ISS)
(35 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 40 P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC) P0CG63 (/IC)
(30 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 40 P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS) P0CG63 (/TAS)
(30 more)
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