The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 272: Serine/threonine-protein kinase STE11

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
2 P23561 (/HDA) P23561 (/HDA)
MAP kinase kinase kinase activity GO:0004709
Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
2 P23561 (/IDA) P23561 (/IDA)
MAP kinase kinase kinase activity GO:0004709
Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
2 Q6FXI1 (/IGI) Q6FXI1 (/IGI)
MAP kinase kinase kinase activity GO:0004709
Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
2 Q6FXI1 (/ISA) Q6FXI1 (/ISA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P23561 (/IPI) P23561 (/IPI)
SAM domain binding GO:0032093
Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.
2 P23561 (/IDA) P23561 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P23561 (/IPI) P23561 (/IPI)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pseudohyphal growth GO:0007124
A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
4 P23561 (/IMP) P23561 (/IMP) Q6FXI1 (/IMP) Q6FXI1 (/IMP)
Osmosensory signaling MAPK cascade GO:0000161
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.
2 P23561 (/IGI) P23561 (/IGI)
Osmosensory signaling MAPK cascade GO:0000161
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.
2 P23561 (/IMP) P23561 (/IMP)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2 P23561 (/IDA) P23561 (/IDA)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2 Q6FXI1 (/IGI) Q6FXI1 (/IGI)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2 P23561 (/IMP) P23561 (/IMP)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2 Q6FXI1 (/ISA) Q6FXI1 (/ISA)
Cell wall integrity MAPK cascade GO:0000196
A MAPK cascade that contributes to cell wall organization or biogenesis.
2 P23561 (/IGI) P23561 (/IGI)
Pheromone-dependent signal transduction involved in conjugation with cellular fusion GO:0000750
A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
2 P23561 (/IMP) P23561 (/IMP)
Signal transduction involved in filamentous growth GO:0001402
Relaying of environmental signals promoting filamentous growth.
2 P23561 (/IMP) P23561 (/IMP)
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
2 P23561 (/IMP) P23561 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P23561 (/HDA) P23561 (/HDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P23561 (/IDA) P23561 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q6FXI1 (/IGI) Q6FXI1 (/IGI)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P23561 (/IMP) P23561 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q6FXI1 (/ISA) Q6FXI1 (/ISA)
Osmosensory signaling pathway via Sho1 osmosensor GO:0007232
A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
2 P23561 (/IGI) P23561 (/IGI)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
2 Q6FXI1 (/IMP) Q6FXI1 (/IMP)
Regulation of transposition, RNA-mediated GO:0010525
Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2 P23561 (/IMP) P23561 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 P23561 (/IMP) P23561 (/IMP)
Cellular hyperosmotic response GO:0071474
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
2 Q6FXI1 (/IMP) Q6FXI1 (/IMP)
Pheromone response MAPK cascade GO:0071507
A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.
2 P23561 (/IDA) P23561 (/IDA)
Pheromone response MAPK cascade GO:0071507
A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.
2 P23561 (/IGI) P23561 (/IGI)
Pheromone response MAPK cascade GO:0071507
A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.
2 P23561 (/IMP) P23561 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P23561 (/IDA) P23561 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q6FXI1 (/IGI) Q6FXI1 (/IGI)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q6FXI1 (/ISA) Q6FXI1 (/ISA)
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