CATH Superfamily 3.10.20.90
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".
FunFam 205: 2'-5'-oligoadenylate synthase-like protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
3 | Q15646 (/IDA) Q8VI94 (/IDA) Q9Z2F2 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | G3V645 (/ISS) Q8VI94 (/ISS) |
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
2 | G3V645 (/ISS) Q5MYT9 (/ISS) |
2'-5'-oligoadenylate synthetase activity GO:0001730
Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.
|
1 | Q9Z2F2 (/IDA) |
2'-5'-oligoadenylate synthetase activity GO:0001730
Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.
|
1 | Q5MYT9 (/ISS) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q15646 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q8VI94 (/ISO) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q15646 (/HDA) |
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
1 | Q8VI94 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q15646 (/IPI) |
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
|
1 | Q15646 (/TAS) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
2 | G3V645 (/ISS) Q8VI94 (/ISS) |
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
2 | Q5MYT9 (/TAS) Q9Z2F2 (/TAS) |
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
1 | Q9Z2F2 (/IDA) |
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
1 | Q15646 (/IDA) |
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
1 | Q8VI94 (/ISO) |
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
1 | Q15646 (/IDA) |
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
1 | Q8VI94 (/ISO) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | Q15646 (/IDA) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | Q8VI94 (/ISO) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | Q15646 (/TAS) |
Interferon-gamma-mediated signaling pathway GO:0060333
A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
|
1 | Q15646 (/TAS) |
Type I interferon signaling pathway GO:0060337
A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
1 | Q15646 (/TAS) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
2 | G3V645 (/ISS) Q8VI94 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | G3V645 (/ISS) Q8VI94 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q15646 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8VI94 (/ISO) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q15646 (/IDA) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q8VI94 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q15646 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8VI94 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q15646 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8VI94 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q15646 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q15646 (/HDA) |