CATH Superfamily 3.10.20.90
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".
FunFam 199: fermitin family homolog 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
3 | Q32LP0 (/ISS) Q86UX7 (/ISS) Q86UX7 (/ISS) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
2 | Q8K1B8 (/IDA) Q8K1B8 (/IDA) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
2 | Q8K1B8 (/IPI) Q8K1B8 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8K1B8 (/IPI) Q8K1B8 (/IPI) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Leukocyte cell-cell adhesion GO:0007159
The attachment of a leukocyte to another cell via adhesion molecules.
|
4 | Q86UX7 (/IMP) Q86UX7 (/IMP) Q8K1B8 (/IMP) Q8K1B8 (/IMP) |
|
Integrin activation GO:0033622
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
|
4 | Q86UX7 (/IMP) Q86UX7 (/IMP) Q8K1B8 (/IMP) Q8K1B8 (/IMP) |
|
Leukocyte cell-cell adhesion GO:0007159
The attachment of a leukocyte to another cell via adhesion molecules.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Integrin activation GO:0033622
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Regulation of cell-cell adhesion mediated by integrin GO:0033632
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
3 | Q32LP0 (/ISS) Q8K1B8 (/ISS) Q8K1B8 (/ISS) |
|
Platelet aggregation GO:0070527
The adhesion of one platelet to one or more other platelets via adhesion molecules.
|
3 | Q32LP0 (/ISS) Q86UX7 (/ISS) Q86UX7 (/ISS) |
|
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
|
2 | Q86UX7 (/TAS) Q86UX7 (/TAS) |
|
Leukocyte cell-cell adhesion GO:0007159
The attachment of a leukocyte to another cell via adhesion molecules.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q86UX7 (/IMP) Q86UX7 (/IMP) |
|
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
2 | Q86UX7 (/IDA) Q86UX7 (/IDA) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Integrin activation GO:0033622
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
|
2 | Q86UX7 (/IDA) Q86UX7 (/IDA) |
|
Integrin activation GO:0033622
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Regulation of cell-cell adhesion mediated by integrin GO:0033632
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
2 | Q86UX7 (/IDA) Q86UX7 (/IDA) |
|
Regulation of cell-cell adhesion mediated by integrin GO:0033632
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
2 | Q8K1B8 (/IMP) Q8K1B8 (/IMP) |
|
Regulation of cell-cell adhesion mediated by integrin GO:0033632
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
2 | Q86UX7 (/IMP) Q86UX7 (/IMP) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
2 | Q8K1B8 (/ISO) Q8K1B8 (/ISO) |
|
Platelet aggregation GO:0070527
The adhesion of one platelet to one or more other platelets via adhesion molecules.
|
2 | Q86UX7 (/HMP) Q86UX7 (/HMP) |
|
Platelet aggregation GO:0070527
The adhesion of one platelet to one or more other platelets via adhesion molecules.
|
2 | Q8K1B8 (/IMP) Q8K1B8 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Podosome GO:0002102
An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
|
3 | Q32LP0 (/ISS) Q86UX7 (/ISS) Q86UX7 (/ISS) |
|
Podosome GO:0002102
An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
|
2 | Q8K1B8 (/IDA) Q8K1B8 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q86UX7 (/TAS) Q86UX7 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q86UX7 (/HDA) Q86UX7 (/HDA) |
|
Platelet alpha granule lumen GO:0031093
The volume enclosed by the membrane of the platelet alpha granule.
|
2 | Q86UX7 (/TAS) Q86UX7 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q86UX7 (/HDA) Q86UX7 (/HDA) |
