The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 111: Histidine ammonia-lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
3 P21213 (/IDA) P35492 (/IDA) P35492 (/IDA)
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
2 P35492 (/ISO) P35492 (/ISO)
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
1 P42357 (/EXP)
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
1 P21213 (/TAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histidine catabolic process GO:0006548
The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2 P35492 (/IDA) P35492 (/IDA)
Histidine metabolic process GO:0006547
The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
1 P21213 (/TAS)
Histidine catabolic process GO:0006548
The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
1 P42357 (/TAS)
Hematopoietic stem cell differentiation GO:0060218
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
1 A4FUP1 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P21213 (/TAS) P42357 (/TAS)
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