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CATH Superfamily 3.10.20.80

Translation initiation factor 3 (IF-3), N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Translation initiation factor 3 (IF-3), N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Translation initiation factor IF-3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 60 P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI) P0A707 (/IPI)
(50 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
 32 P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA)
(22 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
 32 P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA)
(22 more)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)
Methionyl-initiator methionine tRNA binding GO:1990856
Interacting selectively and non-covalently with methionine-initator methionine tRNA.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
 64 P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP) P0A707 (/IMP)
(54 more)
Formation of translation preinitiation complex GO:0001731
The joining of the small ribosomal subunit, ternary complex, and mRNA.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
 32 P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA)
(22 more)
Positive regulation of formation of translation preinitiation complex GO:1901195
Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 32 P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA) P0A707 (/IDA)
(22 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 32 P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA) P0A707 (/HDA)
(22 more)
Translation initiation complex GO:0070992
A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
 32 P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP) P0A708 (/IMP)
(22 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 6 P9WKJ9 (/HDA) P9WKJ9 (/HDA) P9WKJ9 (/HDA) P9WKJ9 (/HDA) P9WKJ9 (/HDA) P9WKJ9 (/HDA)