The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: NADH-quinone oxidoreductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferredoxin hydrogenase activity GO:0008901
Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
4 Q3Z858 (/ISS) Q3Z858 (/ISS) Q3Z8I1 (/ISS) Q603S5 (/ISS)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
3 Q3Z858 (/ISS) Q3Z858 (/ISS) Q3Z8I1 (/ISS)
Oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor GO:0016696
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.
2 Q749M2 (/ISS) Q749M2 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
3 Q603S5 (/ISS) Q749M2 (/ISS) Q749M2 (/ISS)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
1 Q9N4Y8 (/IC)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferredoxin hydrogenase complex GO:0009375
An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.
3 Q3Z858 (/ISS) Q3Z858 (/ISS) Q3Z8I1 (/ISS)
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
1 Q9N4Y8 (/ISS)