The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutamine synthetase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Glutamine synthetase, type I

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamine synthetase. [EC: 6.3.1.2]
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
  • Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.
  • Several types have been described, differing in their oligomeric structures and cofactor requirements.
14 A0A1W0VN50 A0A1W0VN50 A0A1Y3E590 A0A1Y3E590 A0A1Y3E590 A0A2J9KJN4 A0A2J9KJN4 A0A2J9KJN4 O66514 P94845
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