The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Polyketide synthase dehydratase
".
FunFam 2: Fatty acid synthase
There are 8 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
3-oxoacyl-[acyl-carrier-protein] reductase.
[EC: 1.1.1.100]
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
Beta-ketoacyl-[acyl-carrier-protein] synthase I.
[EC: 2.3.1.41]
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl- [acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
Oleoyl-[acyl-carrier-protein] hydrolase.
[EC: 3.1.2.14]
Oleoyl-[acyl-carrier-protein] + H(2)O = [acyl-carrier-protein] + oleate.
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
Fatty-acid synthase system.
[EC: 2.3.1.85]
Acetyl-CoA + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + (n+1) CoA + n CO(2) + 2n NADP(+).
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific).
[EC: 1.3.1.39]
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADPH.
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
3-hydroxyacyl-[acyl-carrier-protein] dehydratase.
[EC: 4.2.1.59]
A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl- carrier protein] + H(2)O.
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
[Acyl-carrier-protein] S-malonyltransferase.
[EC: 2.3.1.39]
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier- protein].
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |
[Acyl-carrier-protein] S-acetyltransferase.
[EC: 2.3.1.38]
Acetyl-CoA + [acyl-carrier-protein] = CoA + acetyl-[acyl-carrier- protein].
|
5 | P12276 P12785 P19096 P49327 Q71SP7 |