The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Hotdog Thioesterase
".
FunFam 46: Acyl-coenzyme A thioesterase THEM4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Palmitoyl-CoA hydrolase activity GO:0016290
Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
|
4 | A1A4L1 (/ISS) Q3UUI3 (/ISS) Q566R0 (/ISS) Q9CQJ0 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q5T1C6 (/IPI) Q8N1Q8 (/IPI) |
|
Palmitoyl-CoA hydrolase activity GO:0016290
Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
|
2 | Q5T1C6 (/IDA) Q8N1Q8 (/IDA) |
|
Palmitoyl-CoA hydrolase activity GO:0016290
Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
|
2 | Q3UUI3 (/ISO) Q9CQJ0 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
3 | A1A4L1 (/ISS) Q3UUI3 (/ISS) Q566R0 (/ISS) |
|
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
|
3 | A1A4L1 (/ISS) Q3UUI3 (/ISS) Q566R0 (/ISS) |
|
Regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108
Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
|
3 | A1A4L1 (/ISS) Q3UUI3 (/ISS) Q566R0 (/ISS) |
|
Acyl-CoA metabolic process GO:0006637
The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
|
2 | Q5T1C6 (/TAS) Q8N1Q8 (/TAS) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | Q5T1C6 (/IDA) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | Q3UUI3 (/ISO) |
|
Long-chain fatty-acyl-CoA metabolic process GO:0035336
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
|
1 | Q8N1Q8 (/IDA) |
|
Long-chain fatty-acyl-CoA metabolic process GO:0035336
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
|
1 | Q9CQJ0 (/ISO) |
|
Long-chain fatty-acyl-CoA metabolic process GO:0035336
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
|
1 | Q9CQJ0 (/ISS) |
|
Cardiolipin acyl-chain remodeling GO:0035965
Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.
|
1 | Q9CQJ0 (/IMP) |
|
Cardiolipin acyl-chain remodeling GO:0035965
Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.
|
1 | Q8N1Q8 (/ISS) |
|
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
|
1 | Q5T1C6 (/IMP) |
|
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
|
1 | Q3UUI3 (/ISO) |
|
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q5T1C6 (/TAS) |
|
Regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108
Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
|
1 | Q5T1C6 (/IMP) |
|
Regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108
Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
|
1 | Q3UUI3 (/ISO) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | A1A4L1 (/ISS) Q3UUI3 (/ISS) Q566R0 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q3UUI3 (/HDA) Q9CQJ0 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | A1A4L1 (/ISS) Q566R0 (/ISS) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | Q5T1C6 (/TAS) Q8N1Q8 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q5T1C6 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q3UUI3 (/ISO) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q8N1Q8 (/IDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q9CQJ0 (/ISO) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q9CQJ0 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q5T1C6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q3UUI3 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q5T1C6 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q5T1C6 (/TAS) |
