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CATH Superfamily 3.10.110.10

Ubiquitin Conjugating Enzyme

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 66: IMPACT isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
 1 O55091 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 1 O55091 (/IPI)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
 1 O55091 (/IDA)

There are 37 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of protein autophosphorylation GO:0031953
Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Regulation of eIF2 alpha phosphorylation by amino acid starvation GO:0060733
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Positive regulation of translational initiation in response to starvation GO:0071264
Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to UV-C GO:0071494
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to benomyl GO:0072755
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Cellular response to leucine starvation GO:1990253
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
 1 O55091 (/IMP)
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
 1 O55091 (/IDA)
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
 1 O55091 (/IMP)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
 1 O55091 (/IDA)
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
 1 O55091 (/IDA)
Negative regulation of protein autophosphorylation GO:0031953
Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
 1 O55091 (/IDA)
Negative regulation of protein autophosphorylation GO:0031953
Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
 1 O55091 (/IMP)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
 1 O55091 (/IDA)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
 1 O55091 (/IDA)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
 1 O55091 (/IMP)
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
 1 O55091 (/IDA)
Regulation of eIF2 alpha phosphorylation by amino acid starvation GO:0060733
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation.
 1 O55091 (/IMP)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
 1 O55091 (/IDA)
Positive regulation of translational initiation in response to starvation GO:0071264
Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
 1 O55091 (/IMP)
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
 1 O55091 (/IDA)
Cellular response to UV-C GO:0071494
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
 1 O55091 (/IDA)
Cellular response to benomyl GO:0072755
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.
 1 O55091 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
 1 O55091 (/IDA)
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
 1 O55091 (/IMP)
Cellular response to leucine starvation GO:1990253
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
 1 O55091 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
 12 A7YY45 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) A9UMG5 (/ISS) Q5GFD8 (/ISS) Q5GFD9 (/ISS) Q5M8G6 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS) Q642J4 (/ISS)
(2 more)
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
 1 O55091 (/IDA)