The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Ubiquitin-conjugating enzyme E2 Q2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI) Q7Z7E8 (/IPI)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
7 O46068 (/ISS) Q29R09 (/ISS) Q32L27 (/ISS) Q7YQJ9 (/ISS) Q86M59 (/ISS) Q8K2Z8 (/ISS) Q8T3U4 (/ISS)
Ubiquitin conjugating enzyme activity GO:0061631
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
3 Q7TSS2 (/IDA) Q7TSS2 (/IDA) Q8K2Z8 (/IDA)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q8WVN8 (/IDA)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q8K2Z8 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
7 O46068 (/ISS) Q29R09 (/ISS) Q32L27 (/ISS) Q7YQJ9 (/ISS) Q86M59 (/ISS) Q8K2Z8 (/ISS) Q8T3U4 (/ISS)
Suckling behavior GO:0001967
Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Mating behavior GO:0007617
The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Fertilization GO:0009566
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Reproductive system development GO:0061458
The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Prolactin secretion GO:0070459
The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
2 Q7TSS2 (/IMP) Q7TSS2 (/IMP)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q8WVN8 (/TAS)
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
1 Q8WVN8 (/IDA)
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
1 Q8K2Z8 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8WVN8 (/TAS)
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