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CATH Superfamily 3.10.110.10

Ubiquitin Conjugating Enzyme

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30: AKT-interacting protein-like isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 12 Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI) Q9H8T0 (/IPI)
(2 more)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
 25 B5X1G6 (/ISS) B5X1G6 (/ISS) Q28IA3 (/ISS) Q498F8 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS)
(15 more)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
 25 B5X1G6 (/ISS) B5X1G6 (/ISS) Q28IA3 (/ISS) Q498F8 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS)
(15 more)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
 25 B5X1G6 (/ISS) B5X1G6 (/ISS) Q28IA3 (/ISS) Q498F8 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS)
(15 more)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
 25 B5X1G6 (/ISS) B5X1G6 (/ISS) Q28IA3 (/ISS) Q498F8 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS)
(15 more)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
 12 Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA)
(2 more)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
 12 Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP)
(2 more)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
 12 Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP)
(2 more)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
 12 Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP)
(2 more)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
 12 Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA)
(2 more)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
 12 Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP) Q9H8T0 (/IMP)
(2 more)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
 2 Q64362 (/ISO) Q64362 (/ISO)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
 2 Q64362 (/ISO) Q64362 (/ISO)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
 2 Q64362 (/ISO) Q64362 (/ISO)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
 2 Q64362 (/ISO) Q64362 (/ISO)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
 2 Q64362 (/ISO) Q64362 (/ISO)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
 2 Q64362 (/ISO) Q64362 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
 25 B5X1G6 (/ISS) B5X1G6 (/ISS) Q28IA3 (/ISS) Q498F8 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS) Q4R5E1 (/ISS)
(15 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 12 Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA)
(2 more)
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
 12 Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA) Q9H8T0 (/IDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 2 Q64362 (/ISO) Q64362 (/ISO)
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
 2 Q64362 (/ISO) Q64362 (/ISO)