The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ubiquitin Conjugating Enzyme
".
FunFam 2: Ubiquitin-conjugating enzyme E2 D3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
623 |
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
(613 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
453 |
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
(443 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
430 |
A5PKP9 (/IDA)
A5PKP9 (/IDA)
A5PKP9 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
D3ZDK2 (/IDA)
(420 more) |
|
Ubiquitin conjugating enzyme activity GO:0061631
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
|
328 |
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(318 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
190 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(180 more) |
|
Ubiquitin conjugating enzyme activity GO:0061631
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
|
186 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(176 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
125 |
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
(115 more) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
78 |
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
P25867 (/IPI)
(68 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
63 |
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(53 more) |
|
Ubiquitin conjugating enzyme activity GO:0061631
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
|
63 |
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
(53 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | Q57W45 (/ISM) Q57W45 (/ISM) Q57W45 (/ISM) |
|
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
|
3 | A5PKP9 (/IPI) A5PKP9 (/IPI) A5PKP9 (/IPI) |
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
3 | A5PKP9 (/IDA) A5PKP9 (/IDA) A5PKP9 (/IDA) |
There are 68 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
498 |
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
(488 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
310 |
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(300 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
308 |
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
(298 more) |
|
Protein K11-linked ubiquitination GO:0070979
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
|
245 |
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
(235 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
244 |
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
P61078 (/ISS)
(234 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
224 |
A5PKP9 (/IDA)
A5PKP9 (/IDA)
A5PKP9 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(214 more) |
|
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
204 |
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
(194 more) |
|
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
190 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(180 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
186 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(176 more) |
|
MyD88-independent toll-like receptor signaling pathway GO:0002756
Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
TRIF-dependent toll-like receptor signaling pathway GO:0035666
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
137 |
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
P35129 (/IDA)
(127 more) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
125 |
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
P61077 (/TAS)
(115 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
125 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(115 more) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
125 |
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
(115 more) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
125 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(115 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
122 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(112 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
122 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(112 more) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
122 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(112 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
122 |
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
(112 more) |
|
Protein K11-linked ubiquitination GO:0070979
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
|
79 |
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
(69 more) |
|
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
|
68 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(58 more) |
|
Protein K11-linked ubiquitination GO:0070979
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
|
65 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(55 more) |
|
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
65 |
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
(55 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
64 |
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
(54 more) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
64 |
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
P61080 (/ISS)
(54 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
63 |
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
(53 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
|
63 |
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(53 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
63 |
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
P25867 (/ISS)
(53 more) |
|
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Regulation of R7 cell differentiation GO:0045676
Any process that modulates the frequency, rate or extent of R7 differentiation.
|
63 |
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
P25867 (/IGI)
(53 more) |
|
Female germ-line stem cell asymmetric division GO:0048132
The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Chromosome organization GO:0051276
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
|
63 |
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
P25867 (/IMP)
(53 more) |
|
Protein linear polyubiquitination GO:0097039
A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
|
63 |
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
P25867 (/IDA)
(53 more) |
|
Protein monoubiquitination GO:0006513
Addition of a single ubiquitin group to a protein.
|
61 |
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
P61077 (/IDA)
(51 more) |
|
Protein monoubiquitination GO:0006513
Addition of a single ubiquitin group to a protein.
|
61 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(51 more) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
61 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(51 more) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
61 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(51 more) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
61 |
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
(51 more) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
61 |
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
(51 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
61 |
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
P61079 (/ISO)
(51 more) |
|
Cellular response to mercury ion GO:0071288
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
|
61 |
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
P61078 (/IEP)
(51 more) |
|
Regulation of mitotic cell cycle phase transition GO:1901990
Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
|
61 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(51 more) |
|
Positive regulation of protein polyubiquitination GO:1902916
Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.
|
61 |
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
P61080 (/IGI)
(51 more) |
|
Positive regulation of protein targeting to mitochondrion GO:1903955
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
|
61 |
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
P61077 (/HMP)
(51 more) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
22 |
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
Q8I607 (/ISS)
(12 more) |
|
Protein K29-linked ubiquitination GO:0035519
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.
|
18 |
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
(8 more) |
|
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
|
18 |
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
(8 more) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
18 |
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
(8 more) |
|
Protein K6-linked ubiquitination GO:0085020
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.
|
18 |
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
Q9Y2X8 (/IDA)
(8 more) |
|
Protein K29-linked ubiquitination GO:0035519
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.
|
4 | Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) |
|
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
|
4 | Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
4 | Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) |
|
Protein K6-linked ubiquitination GO:0085020
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.
|
4 | Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) Q6ZWY6 (/ISO) |
|
Cellular response to arsenite(3-) GO:1903841
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.
|
4 | P70711 (/IEP) P70711 (/IEP) P70711 (/IEP) P70711 (/IEP) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
3 | Q57W45 (/ISM) Q57W45 (/ISM) Q57W45 (/ISM) |
|
Pronephric nephron tubule development GO:0039020
The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.
|
3 | A5PKP9 (/IMP) A5PKP9 (/IMP) A5PKP9 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
249 |
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
P25867 (/TAS)
(239 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
186 |
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
P51668 (/TAS)
(176 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
183 |
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
D3ZDK2 (/ISS)
(173 more) |
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
125 |
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
(115 more) |
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
125 |
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
(115 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
125 |
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
(115 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
125 |
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
(115 more) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
125 |
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
P61077 (/HDA)
(115 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
83 |
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
P51668 (/IDA)
(73 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
61 |
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
P61080 (/ISO)
(51 more) |