The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ubiquitin Conjugating Enzyme
".
FunFam 127: Component of the ESCRT-I complex
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) |
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
6 | P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein targeting to membrane GO:0006612
The process of directing proteins towards a membrane, usually using signals contained within the protein.
|
6 | P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) |
|
Protein targeting to vacuole GO:0006623
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
|
6 | P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) |
|
Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
|
6 | P25604 (/IC) P25604 (/IC) P25604 (/IC) P25604 (/IC) P25604 (/IC) P25604 (/IC) |
|
Late endosome to vacuole transport GO:0045324
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
|
6 | P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) |
|
Negative regulation of protein polyubiquitination GO:1902915
Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.
|
6 | P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) |
|
ATP export GO:1904669
The directed movement of ATP out of a cell or organelle.
|
6 | P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) P25604 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ESCRT I complex GO:0000813
An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
|
6 | P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) |
|
ESCRT I complex GO:0000813
An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
|
6 | P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) P25604 (/IPI) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
6 | P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | P25604 (/HDA) P25604 (/HDA) P25604 (/HDA) P25604 (/HDA) P25604 (/HDA) P25604 (/HDA) |
|
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
6 | P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) P25604 (/IDA) |