The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mannose-Binding Protein A, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 10: C-type lectin domain family 3 member A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
24 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(14 more)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
24 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(14 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
5 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
5 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA)
Kringle domain binding GO:0036143
Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
5 P05452 (/IPI) P05452 (/IPI) P05452 (/IPI) P05452 (/IPI) P05452 (/IPI)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
2 O75596 (/TAS) P43025 (/TAS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P43025 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P43025 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P43025 (/IPI)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P43025 (/ISO)
Kringle domain binding GO:0036143
Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
1 P43025 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
28 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(18 more)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
23 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(13 more)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
7 D3ZUU6 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P43025 (/IEP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
6 P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) Q2KIS7 (/IEP)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
5 P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
5 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA)
Cellular response to organic substance GO:0071310
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
5 P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP)
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
5 P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP) P05452 (/IEP)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1 P43025 (/IMP)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1 O75596 (/TAS)
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
1 P43025 (/IDA)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 P43025 (/ISO)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Granular component GO:0001652
A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
24 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(14 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
24 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(14 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
23 D3ZUU6 (/ISS) F1SRC8 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS) F6T0W5 (/ISS)
(13 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P43025 (/IDA)
Granular component GO:0001652
A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
5 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 P05452 (/NAS) P05452 (/NAS) P05452 (/NAS) P05452 (/NAS) P05452 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA) P05452 (/IDA)
Platelet dense granule lumen GO:0031089
The volume enclosed by the membrane of the platelet dense granule.
5 P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS) P05452 (/TAS)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
5 P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA) P05452 (/HDA)
Granular component GO:0001652
A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
1 P43025 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P43025 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P43025 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P43025 (/ISO)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 P43025 (/TAS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...