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CATH Superfamily 2.80.10.50

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 288: Aldos-2-ulose dehydratase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aldos-2-ulose dehydratase. [EC: 4.2.1.110]
1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H(2)O.
  • This enzyme catalyzes two of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose.
  • Aldose-2-uloses such as 2-dehydroglucose can also act as substrates, but more slowly.
  • This is a bifunctional enzyme that acts as both a lyase and as an isomerase.
  • Differs from EC 4.2.1.111, which can carry out only reaction 1, is inhibited by its product and requires metal ions for activity.
 1 P84193
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