The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Copper amine oxidase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Amine oxidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 29 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Primary amine oxidase activity GO:0008131
Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Quinone binding GO:0048038
Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
11 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS) Q9TRC7 (/ISS)
(1 more)
Diamine oxidase activity GO:0052597
Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.
11 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS) Q9TRC7 (/ISS)
(1 more)
Diamine oxidase activity GO:0052597
Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.
5 P19801 (/IDA) P36633 (/IDA) Q96X16 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
4 P19801 (/IDA) P36633 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Primary amine oxidase activity GO:0008131
Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
3 P19801 (/IDA) Q5B038 (/IDA) Q5B038 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 P19801 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 Q8JZQ5 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P19801 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q8JZQ5 (/ISO)
Primary amine oxidase activity GO:0008131
Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
1 Q8JZQ5 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 Q8JZQ5 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P36633 (/TAS)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P19801 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 Q8JZQ5 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P19801 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q8JZQ5 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P19801 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q8JZQ5 (/ISO)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P19801 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q8JZQ5 (/ISO)
Quinone binding GO:0048038
Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
1 P19801 (/IDA)
Quinone binding GO:0048038
Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
1 Q8JZQ5 (/ISO)
Diamine oxidase activity GO:0052597
Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.
1 Q8JZQ5 (/ISO)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Cellular response to histamine GO:0071420
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Cellular response to azide GO:0097185
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Cellular response to copper ion starvation GO:0035874
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
11 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS) Q9TRC7 (/ISS)
(1 more)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
11 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS) Q9TRC7 (/ISS)
(1 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
10 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS) Q9TRC7 (/ISS) Q9TRC7 (/ISS)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
5 G1T7Z9 (/IDA) P19801 (/IDA) P36633 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
5 P19801 (/IDA) P36633 (/IDA) Q96X16 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
3 P19801 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Peptidyl-lysine oxidation GO:0018057
The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.
2 Q5B038 (/IDA) Q5B038 (/IDA)
Peptide cross-linking GO:0018149
The formation of a covalent cross-link between or within protein chains.
2 Q5B038 (/IDA) Q5B038 (/IDA)
Cellular response to copper ion starvation GO:0035874
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
2 P19801 (/IDA) P36633 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 P19801 (/TAS)
Amiloride transport GO:0015898
The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.
1 Q8JZQ5 (/ISO)
Cellular response to copper ion starvation GO:0035874
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
1 Q8JZQ5 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q8JZQ5 (/ISO)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
1 P19801 (/TAS)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
1 Q8JZQ5 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 Q8JZQ5 (/ISO)
Cellular response to inorganic substance GO:0071241
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 Q96X16 (/IDA)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 P19801 (/IDA)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 Q8JZQ5 (/ISO)
Cellular response to histamine GO:0071420
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
1 P19801 (/IDA)
Cellular response to histamine GO:0071420
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
1 Q8JZQ5 (/ISO)
Cellular response to heparin GO:0071504
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
1 P19801 (/TAS)
Cellular response to azide GO:0097185
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
1 P19801 (/IDA)
Cellular response to azide GO:0097185
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
1 Q8JZQ5 (/ISO)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) F7CDQ6 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS)
(3 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P36633 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
12 F1PVS5 (/ISS) F6TU34 (/ISS) F6UPB3 (/ISS) G1M630 (/ISS) G1Q748 (/ISS) G1T7Z9 (/ISS) P19801 (/ISS) Q3MHQ1 (/ISS) Q5R5H9 (/ISS) Q8JZQ5 (/ISS)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P19801 (/IDA) Q9TRC7 (/IDA) Q9TRC7 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P19801 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P19801 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q8JZQ5 (/ISO)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 P19801 (/NAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8JZQ5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P19801 (/TAS)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
1 P36633 (/IDA)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
1 Q8JZQ5 (/ISO)
Specific granule lumen GO:0035580
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
1 P19801 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P19801 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P19801 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q8JZQ5 (/ISO)
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