The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glucose Permease (Domain IIA)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: PTS system glucose-specific IIA component

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
175 P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI)
(165 more)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
175 P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA)
(165 more)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
175 P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP)
(165 more)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
10 Q81MH9 (/ISS) Q81MH9 (/ISS) Q81MH9 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
175 P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA)
(165 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
175 P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP)
(165 more)
Negative regulation of carbohydrate metabolic process GO:0045912
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
175 P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA)
(165 more)
Negative regulation of carbohydrate metabolic process GO:0045912
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
175 P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI) P69783 (/IPI)
(165 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
10 Q81MH9 (/ISS) Q81MH9 (/ISS) Q81MH9 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
10 Q81MH9 (/ISS) Q81MH9 (/ISS) Q81MH9 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS) Q9KTD8 (/ISS)
Sucrose transport GO:0015770
The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.
3 Q81MH9 (/ISS) Q81MH9 (/ISS) Q81MH9 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
178 P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA)
(168 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
175 P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA)
(165 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
175 P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA) P69783 (/HDA)
(165 more)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
175 P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA) P69783 (/IDA)
(165 more)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
175 P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP) P69783 (/IMP)
(165 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
19 P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA) P08722 (/IDA)
(9 more)