The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GMP phosphodiesterase, delta subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: protein unc-119 homolog A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI) A6NIH7 (/IPI)
(5 more)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
12 A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA)
(2 more)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
10 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q66JA9 (/ISS) Q66JA9 (/ISS) Q6INE2 (/ISS) Q8C4B4 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
3 Q8C4B4 (/ISO) Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
12 A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA)
(2 more)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
12 A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP) A6NIH7 (/IMP)
(2 more)
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q66JA9 (/ISS) Q66JA9 (/ISS) Q6INE2 (/ISS) Q8C4B4 (/ISS)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
6 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Kupffer's vesicle development GO:0070121
The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
6 A1L1X3 (/IMP) Q1RM42 (/IMP) Q504L3 (/IMP) Q6GML9 (/IMP) Q90Z08 (/IMP) Q90Z09 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
5 A1L1X3 (/IMP) Q1RM42 (/IMP) Q504L3 (/IMP) Q6GML9 (/IMP) Q90Z09 (/IMP)
Negative regulation of clathrin-dependent endocytosis GO:1900186
Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.
5 O19177 (/ISS) Q13432 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS)
Negative regulation of caveolin-mediated endocytosis GO:2001287
Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.
5 O19177 (/ISS) Q13432 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS)
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q8C4B4 (/ISO) Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9Z2R6 (/IMP) Q9Z2R6 (/IMP)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Negative regulation of clathrin-dependent endocytosis GO:1900186
Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.
2 Q9Z2R6 (/IMP) Q9Z2R6 (/IMP)
Negative regulation of caveolin-mediated endocytosis GO:2001287
Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.
2 Q9Z2R6 (/IMP) Q9Z2R6 (/IMP)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
1 Q13432 (/IMP)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q13432 (/TAS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 Q90Z08 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 Q13432 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 Q13432 (/TAS)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q8C4B4 (/ISO)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
1 Q13432 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS)
(2 more)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
11 A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS) A6NIH7 (/TAS)
(1 more)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
11 A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA) A6NIH7 (/IDA)
(1 more)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
6 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
6 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
6 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
6 O19177 (/ISS) Q3SYR2 (/ISS) Q3SYR2 (/ISS) Q62885 (/ISS) Q9Z2R6 (/ISS) Q9Z2R6 (/ISS)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
4 Q66JA9 (/ISS) Q66JA9 (/ISS) Q6INE2 (/ISS) Q8C4B4 (/ISS)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
2 Q9Z2R6 (/ISO) Q9Z2R6 (/ISO)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 Q13432 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q13432 (/IDA)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
1 Q8C4B4 (/ISO)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
1 Q13432 (/IDA)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
1 Q13432 (/IDA)
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