The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Coagulation Factor XIII, subunit A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Rho GDP-dissociation inhibitor 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
40 P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI) P52565 (/IPI)
(30 more)
Rho GDP-dissociation inhibitor activity GO:0005094
Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
22 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(12 more)
Rho GDP-dissociation inhibitor activity GO:0005094
Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
19 P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA)
(9 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
7 P52566 (/IMP) P52566 (/IMP) P52566 (/IMP) P52566 (/IMP) P52566 (/IMP) P52566 (/IMP) P52566 (/IMP)
Rho GDP-dissociation inhibitor activity GO:0005094
Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
7 P19803 (/ISS) P19803 (/ISS) P19803 (/ISS) Q61599 (/ISS) Q61599 (/ISS) Q9TU03 (/ISS) Q9TU03 (/ISS)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
7 P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
4 Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
4 Q5XI73 (/IPI) Q5XI73 (/IPI) Q5XI73 (/IPI) Q5XI73 (/IPI)
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
4 Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
4 Q61599 (/ISS) Q61599 (/ISS) Q9TU03 (/ISS) Q9TU03 (/ISS)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
4 Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Rho GDP-dissociation inhibitor activity GO:0005094
Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
3 O14224 (/ISO) Q61599 (/ISO) Q61599 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q61599 (/ISO) Q61599 (/ISO)
GDP-dissociation inhibitor activity GO:0005092
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
2 Q62160 (/IDA) Q62160 (/IDA)
GTPase regulator activity GO:0030695
Modulates the rate of GTP hydrolysis by a GTPase.
2 Q62160 (/IDA) Q62160 (/IDA)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
2 Q61599 (/ISO) Q61599 (/ISO)

There are 41 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Semaphorin-plexin signaling pathway GO:0071526
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
33 P19803 (/ISS) P19803 (/ISS) P19803 (/ISS) P52565 (/ISS) P52565 (/ISS) P52565 (/ISS) P52565 (/ISS) P52565 (/ISS) P52565 (/ISS) P52565 (/ISS)
(23 more)
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
22 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(12 more)
Regulation of small GTPase mediated signal transduction GO:0051056
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
22 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(12 more)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
20 P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP)
(10 more)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
20 P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP) P52565 (/IMP)
(10 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
13 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(3 more)
Negative regulation of axonogenesis GO:0050771
Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.
13 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(3 more)
Positive regulation of axonogenesis GO:0050772
Any process that activates or increases the frequency, rate or extent of axonogenesis.
13 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(3 more)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
8 Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
8 Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP) Q12434 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
8 Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI) Q12434 (/IPI)
Regulation of vacuole fusion, non-autophagic GO:0032889
Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
8 Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
7 P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
7 P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA)
Negative regulation of trophoblast cell migration GO:1901164
Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.
7 P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
6 Q62160 (/IDA) Q62160 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
6 Q61599 (/ISO) Q61599 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
6 Q61599 (/ISO) Q61599 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Cellular response to redox state GO:0071461
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
5 Q5M860 (/IEP) Q5XI73 (/IEP) Q5XI73 (/IEP) Q5XI73 (/IEP) Q5XI73 (/IEP)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
4 Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
4 Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
4 Q61599 (/ISS) Q61599 (/ISS) Q9TU03 (/ISS) Q9TU03 (/ISS)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
4 Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP) Q5XI73 (/IMP)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
4 Q5XI73 (/IEP) Q5XI73 (/IEP) Q5XI73 (/IEP) Q5XI73 (/IEP)
Semaphorin-plexin signaling pathway GO:0071526
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
4 Q99PT1 (/IMP) Q99PT1 (/IMP) Q99PT1 (/IMP) Q99PT1 (/IMP)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
4 Q61599 (/ISS) Q61599 (/ISS) Q9TU03 (/ISS) Q9TU03 (/ISS)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
3 P19803 (/ISS) P19803 (/ISS) P19803 (/ISS)
Blastocyst hatching GO:0001835
The hatching of the cellular blastocyst from the zona pellucida.
2 Q62160 (/IMP) Q62160 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
2 Q6P3J2 (/IMP) Q802W6 (/IMP)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2 Q99819 (/TAS) Q99819 (/TAS)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 Q5AND4 (/IMP) Q5AND4 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q5AND4 (/IMP) Q5AND4 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
2 Q5AND4 (/IMP) Q5AND4 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
2 Q5AND4 (/IMP) Q5AND4 (/IMP)
Negative regulation of trophoblast cell migration GO:1901164
Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.
2 Q61599 (/ISO) Q61599 (/ISO)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 O14224 (/ISO)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
1 O14224 (/ISO)

There are 26 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
26 F1T0H7 (/IDA) F1T0H7 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) P52566 (/IDA) Q12434 (/IDA)
(16 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
23 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(13 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
20 P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS) P52565 (/TAS)
(10 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
20 P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA) P52565 (/HDA)
(10 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
11 Q5M860 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q62160 (/IDA) Q62160 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 O14224 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
9 P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) Q99819 (/TAS) Q99819 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 Q61599 (/ISO) Q61599 (/ISO) Q62160 (/ISO) Q62160 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA) Q12434 (/HDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
8 Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
8 Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA) Q12434 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS) P52566 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
6 Q61599 (/ISO) Q61599 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
4 Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA) Q99PT1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 F1T0H7 (/IDA) F1T0H7 (/IDA) Q99819 (/IDA) Q99819 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
4 Q5XI73 (/EXP) Q5XI73 (/EXP) Q5XI73 (/EXP) Q5XI73 (/EXP)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
4 Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA) Q5XI73 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
4 Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO) Q99PT1 (/ISO)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
3 P19803 (/ISS) P19803 (/ISS) P19803 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q5AND4 (/IDA) Q5AND4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q61599 (/ISS) Q61599 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q62160 (/ISO) Q62160 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O14224 (/HDA)
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