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CATH Superfamily 2.70.40.10

Deoxyuridine triphosphatase (dUTPase)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: dCTP deaminase, dUMP-forming

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DCTP deaminase (dUMP-forming). [EC: 3.5.4.30]
dCTP + 2 H(2)O = dUMP + diphosphate + NH(3).
  • Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP, cytosine or deoxycytosine are not deaminated.
  • While most bacteria require two enzymes to form dUMP from dCTP (EC 3.5.4.13 and EC 3.6.1.23), the archaeon Methanocaldococcus jannaschii uses a single enzyme to carry out both functions.
  • This enzyme can also act as a dUTP diphosphatase, but more slowly.
 566 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2 A0A098N2N2
(556 more...)
DCTP deaminase. [EC: 3.5.4.13]
dCTP + H(2)O = dUTP + NH(3).
    		 1 Q7UU94