The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: Deoxyuridine triphosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DUTP diphosphatase activity GO:0004170
Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.
4 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO) Q9P6Q5 (/ISO)
DUTP diphosphatase activity GO:0004170
Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.
3 P70583 (/IDA) Q8IPB1 (/IDA) Q9V3I1 (/IDA)
Receptor inhibitor activity GO:0030547
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Pyrimidine deoxyribonucleotide binding GO:0032556
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9STG6 (/IPI) Q9V3I1 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9STG6 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 P33316 (/HDA)
DUTP diphosphatase activity GO:0004170
Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.
1 Q54BW5 (/ISS)
DUTP diphosphatase activity GO:0004170
Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.
1 P33316 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P33316 (/IPI)
Receptor inhibitor activity GO:0030547
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased.
1 P70583 (/IDA)
Pyrimidine deoxyribonucleotide binding GO:0032556
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
1 P70583 (/IDA)
DITP diphosphatase activity GO:0035870
Catalysis of the reaction: dITP + H2O = dIMP + diphosphate.
1 Q9P6Q5 (/ISO)
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
1 P70583 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DUTP catabolic process GO:0046081
The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.
4 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO) Q9P6Q5 (/ISO)
DUMP biosynthetic process GO:0006226
The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Regulation of protein heterodimerization activity GO:0043497
Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
DUTP metabolic process GO:0046080
The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.
2 Q8IPB1 (/IDA) Q9V3I1 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 P70583 (/IEP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 P33316 (/TAS)
DUMP biosynthetic process GO:0006226
The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).
1 P70583 (/IDA)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
1 P33316 (/TAS)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
1 Q9STG6 (/IMP)
Pyrimidine deoxyribonucleoside triphosphate catabolic process GO:0009213
The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
1 Q54BW5 (/ISS)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P70583 (/IEP)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
1 P33316 (/TAS)
DITP catabolic process GO:0035863
The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
1 Q9P6Q5 (/ISO)
Regulation of protein heterodimerization activity GO:0043497
Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
1 P70583 (/IDA)
DUTP catabolic process GO:0046081
The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.
1 P70583 (/IDA)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
1 P70583 (/IDA)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 A0A0C4DGL3 (/IDA) H0YKC5 (/IDA) H0YNW5 (/IDA) P33316 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8IPB1 (/HDA) Q9P6Q5 (/HDA) Q9V3I1 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P70583 (/IDA) Q8IPB1 (/IDA) Q9V3I1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P70583 (/IDA) Q8IPB1 (/IDA) Q9V3I1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q8VCG1 (/HDA) Q9CQ43 (/HDA) Q9JJ44 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q8VCG1 (/ISO) Q9CQ43 (/ISO) Q9JJ44 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P70583 (/IDA) Q9STG6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8IPB1 (/HDA) Q9V3I1 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P33316 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P33316 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P33316 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9P6Q5 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P33316 (/HDA)