The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Topoisomerase I, domain 3
".
FunFam 6: DNA topoisomerase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
9 | P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) |
|
DNA topoisomerase type I activity GO:0003917
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
|
9 | P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of ribonuclease activity GO:0060701
Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
|
9 | P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) P9WG49 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
9 | P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) P9WG49 (/HDA) |