The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Topoisomerase I, domain 3
".
FunFam 13: DNA topoisomerase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
4 | Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) |
|
DNA topoisomerase type I activity GO:0003917
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
|
4 | Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA topological change GO:0006265
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
|
4 | Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) |
|
DNA unwinding involved in DNA replication GO:0006268
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
|
4 | Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) |
|
DNA modification GO:0006304
The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
|
4 | Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) Q383X7 (/ISM) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
4 | Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
4 | Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) Q383X7 (/IDA) |